Subscribe now

Health

A better understanding of PCOS offers fresh hope for new treatments

New insights into polycystic ovary syndrome are revealing more about the causes of this common but misunderstood whole-body condition, and these could lead to new treatments

By Alice Klein

26 January 2023

Polycystic ovary syndrome

Owen Gent

I WAS 19, my face raging with acne, when my dermatologist started asking me questions that seemed to have nothing to do with my skin. “Are your periods regular? Do you have any excess body hair?” he asked. “You may have polycystic ovary syndrome,” he concluded. I had no idea what he was talking about. “It can make it difficult to have children,” he said as he saw me out.

Reeling, I went to my family doctor, who ordered blood tests and an ultrasound of my ovaries that confirmed I had polycystic ovary syndrome, or PCOS. But she admitted she didn’t know much about it, leaving me confused and miserable about this mysterious condition I had suddenly been saddled with.

Many of my friends have recounted similar experiences. Despite PCOS being the most common hormonal condition among women aged 18 to 45 and a leading cause of infertility, it has been hard for us to get a straight answer about what it actually is or what to do about it.

Seventeen years on from my diagnosis, however, the tide is turning. Researchers are finally piecing together the causes of PCOS and it is being taken seriously as a condition that doesn’t just affect the ovaries, but also has cardiovascular, metabolic and psychological repercussions. As a result, the condition is even set to get a different name later this year (see “Misleading moniker”). And what’s more, this clearer understanding is opening up routes to new treatments.

The first doctors to characterise PCOS were Irving Stein and Michael Leventhal at Northwestern University in Chicago. In 1935, they published a report on…

Sign up to our weekly newsletter

Receive a weekly dose of discovery in your inbox! We'll also keep you up to date with New Scientist events and special offers.

Sign up

To continue reading, subscribe today with our introductory offers

View introductory offers

No commitment, cancel anytime*

Offer ends 2nd of July 2024.

*Cancel anytime within 14 days of payment to receive a refund on unserved issues.

Inclusive of applicable taxes (VAT)

or

Existing subscribers

Sign in to your account