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Life

A surprisingly quick enzyme could shift our understanding of evolution

Biological processes such as DNA replication or cellular structure formation may become more accurate when done as quickly as possible, offering new hints into life's origins

By Karmela Padavic-Callaghan

10 June 2024

F0FBHN Spiral strands of DNA on the dark background

An enzyme that helps copy DNA strands like these may be most accurate when working quickly

Alexey Kotelnikov / Alamy Stock Photo

By trying to speed up, molecular processes can become more reliable – a phenomenon that may have helped life evolve from relatively simple chemicals. Understanding how speed plays a role in cellular replication could add a crucial variable to Charles Darwin’s theory of evolution, in which natural selection drives reproductive success.

The finding comes from Kabir Husain at University College London, Riccardo Ravasio at the University of Chicago and their colleagues, who were frustrated by an experiment…

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